As part of the TUM Global Visiting Professor Program, Cholsoon Jang, a leading expert in metabolic research from the University of California, Irvine and a publisher in high-ranking journals Nature, Science, and Cell, visited Munich for one week.
His stay included collaborative lab work with the P04-HyperPig team. The scientists were able to exchange details of the experimental strategy in the direct experimental setup. Jang’s recent publication, “Cross-organ metabolite production and consumption in healthy and atherogenic conditions”, explores organ-specific metabolomics and arterio-venous metabolite gradients, a topic also addressed within HyperMet. During his visit, he shared hands-on expertise in isotope tracing and metabolic flux analysis, contributing to ongoing research on inter-organ metabolic networks in cardiovascular disease and aging.
To seal the future close cooperation, a visit to the Munich Oktoberfest was mandatory.
The final lecture provided insights into current projects of his lab, including the discovery of Nicotinic acid Riboside (NaR) as a circulating metabolite produced by the liver and processed by the kidneys. The presentation also covered the impact of high-fat/high-sucrose diets on inter-organ metabolite exchange in pig models, as well as the role of bile acids in vascular inflammation.
In the subsequent Q&A session, participants discussed publication strategies, the application of AI in metabolomics, and employment practices for PhD students and Postdocs. Concluding this informative, educational, and promising collaborative visit.