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Technical University of Munich

Welcome at the Associate Professorship of Exercise Biology!

Our strategy: Many athletic performances are critically dependent on metabolic function, and physical training is effective in preventing and treating metabolic diseases such as diabetes mellitus and obesity. The Exercise Biology group at the TU Munich therefore aims to investigate topics related to sports and metabolism often with disease relevance. We often use state-of-the-art methods of metabolic research such as arteriovenous metabolomics analyses and metabolic flux analyses as well as methods of molecular sports physiology. Our main goal with this strategy is to mechanistically answer important unanswered questions in the field. We want to discover new phenomena that help athletes optimize their performance, help patients recover, and ultimately help all people who want to stay fit and healthy for a long time.

News

New Paper - Analysis of the relationship between the KRAS G12V oncogene and the Hippo effector YAP1 in embryonal rhabdomyosarcoma (copy 2)

Persistent hyperactivity of the Hippo effector YAP in activated satellite cells is sufficient to cause embryonal rhabdomyosarcoma (ERMS) in mice. In humans, YAP is abundant and nuclear in the majority of ERMS cases, and high YAP expression is associated with poor survival. However, YAP1 is rarely…

New Paper - Stimuli and sensors that initiate skeletal muscle hypertrophy"

One of the most striking adaptations to exercise is the skeletal muscle hypertrophy that occurs in response to resistance exercise. A large body of work shows that a mTORC1-mediated increase of muscle protein synthesis is the key, but not sole. Whilst much of the hypertrophy signaling cascade has…

Advert for Master Thesis: Evidence-based recommendations for training and nutrition in professional Alpine Skiing

In cooperation with the German Skiing Association (DSV), the Chair of Exercise Biology offers two Master Theses dealing with optimisation of training methods and nutrition in professional alpine skiers. More information is provided in the download files. If you are interested, please contact  Prof.…

Advert for Master Thesis: What is the expression of a Warburg effect-associated enzyme in diseased and healthy skeletal muscle?

Nearly 100 years ago Otto Warburg discovered that cancer cell change their metabolism. Today we know that this serves to provide metabolites as substrates for anabolic reaction in fast growing cancer cells. In our preliminary data we noted that a similar metabolic remodelling occurs during…

TUM expedition to the Wildspitze (3768 m)

The TUM module in mountain sports was running for the second time this year. In this module, students attend lectures on topics that range from evidence-based training methods and nutrition for mountain sports to genetic variants that have been naturally selected in Tibetans and people that live on…

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